Gold nano-particles as SERS substrates for CKDu biomarker detection Posted on August 16, 2021January 7, 2022 by Hiran Jayaweera Gold nanoparticles are frequently used for Surface Enhanced Raman spectroscopy. In this project spherical Au nanoparticles of size scales 20 – 40 nm are synthezised and conjugated with antibodies to detect Creatinine.